Combined in vitro IL-12 and IL-15 stimulation promotes cellular immune response in dogs with visceral leishmaniasis.

Combined in vitro IL-12 and IL-15 stimulation promotes cellular immune response in dogs with visceral leishmaniasis.

Domestic dogs are the main reservoir of Leishmania infantum, a causative agent of visceral leishmaniasis (VL). The number of human disease cases is associated with the rate of canine infection. Currently available drugs are not efficient at treating canine leishmaniasis (CanL) and months after the t...

Full description

Bibliographic Details
Main Authors: Sidnei Ferro Costa, Vinícius Oliveira Gomes, Marilene Oliveira Dos Santos Maciel, Larissa Martins Melo, Gabriela Lovizutto Venturin, Jaqueline Poleto Bragato, Gabriela Torres Rebech, Catiule de Oliveira Santos, Bárbara Maria Nascimento de Oliveira, Geraldo Gileno de Sá Oliveira, Valéria Marçal Felix de Lima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008021

Internet

https://doi.org/10.1371/journal.pntd.0008021

Similar Items