Association of MBL2 Exon 1 Polymorphisms With Multibacillary Leprosy

Association of MBL2 Exon 1 Polymorphisms With Multibacillary Leprosy

Mannose-binding lectin (MBL) is a serum protein of innate immunity, with a central role in the activation of the complement system through the lectin pathway. This protein is encoded by MBL2 gene, and single-nucleotide polymorphisms located at exon 1, such as rs5030737 C>T (D variant), rs1800...

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Main Authors: Bruna Tiaki Tiyo, Evelyn Castillo Lima Vendramini, Victor Hugo de Souza, Cristiane Maria Colli, Hugo Vicentin Alves, Ana Maria Sell, Sylmara Bessani Paixão Zucoloto, Jeane Eliete Laguila Visentainer
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
genetic polymorphism
mannose-binding lectin
multibacillary
genetic predisposition to disease
case–control study
gene frequencies
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01927/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.01927/full

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