14-3-3σ regulates β-catenin-mediated mouse embryonic stem cell proliferation by sequestering GSK-3β.

14-3-3σ regulates β-catenin-mediated mouse embryonic stem cell proliferation by sequestering GSK-3β.

Pluripotent embryonic stem cells are considered to be an unlimited cell source for tissue regeneration and cell-based therapy. Investigating the molecular mechanism underlying the regulation of embryonic stem cell expansion is thus important. 14-3-3 proteins are implicated in controlling cell divisi...

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Bibliographic Details
Main Authors: Tzu-Ching Chang, Chia-Chia Liu, En-Wei Hsing, Shu-Man Liang, Ya-Hui Chi, Li-Ying Sung, Shau-Ping Lin, Tang-Long Shen, Bor-Sheng Ko, B Linju Yen, Shaw-Fang Yet, Kenneth K Wu, Jun-Yang Liou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3387134?pdf=render

Internet

http://europepmc.org/articles/PMC3387134?pdf=render

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