Real-time finite element analysis allows homogenization of tissue scale strains and reduces variance in a mouse defect healing model

Abstract Mechanical loading allows both investigation into the mechano-regulation of fracture healing as well as interventions to improve fracture-healing outcomes such as delayed healing or non-unions. However, loading is seldom individualised or even targeted to an effective mechanical stimulus le...

Full description

Bibliographic Details
Main Authors: Graeme R. Paul, Esther Wehrle, Duncan C. Tourolle, Gisela A. Kuhn, Ralph Müller
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92961-y