Expression of RAGE and HMGB1 in thymic epithelial tumors, thymic hyperplasia and regular thymic morphology.

Recently, a role of the receptor for advanced glycation endproducts (RAGE) in myasthenia gravis was described. RAGE and its ligand high mobility group box 1 (HMGB1) play key roles in autoimmunity and cancer. To test whether these molecules are involved in patients with thymic abnormalities we applie...

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Bibliographic Details
Main Authors: Bernhard Moser, Stefan Janik, Ana-Iris Schiefer, Leonhard Müllauer, Christine Bekos, Anke Scharrer, Michael Mildner, Ferenc Rényi-Vámos, Walter Klepetko, Hendrik Jan Ankersmit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3976415?pdf=render