Molecular docking of ZSTK474 derivatives as potential PI3K-delta inhibitory agents

Molecular docking of ZSTK474 derivatives as potential PI3K-delta inhibitory agents

<p class="Abstract">The phosphatidylinositol 3-kinase delta (PI3Kd) controls a range of cellular processes. Its overexpression is found in many human tumors. PI3Kd inhibitors are potential anticancer agents and anti-inflammatory agents for treatment of rheumatoid arthritis. Derivativ...

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Bibliographic Details
Main Authors: Liudmyla K. Sviatenko, Oksana V. Tereshchenko
Format: Article
Language:English
Published: Oles Honchar Dnipropetrovsk National University 2014-12-01
Series:Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Hìmìâ
Subjects:
molecular docking
binding energy
binding site
inhibitors
Online Access:http://chemistry.dnu.dp.ua/article/view/24563

Internet

http://chemistry.dnu.dp.ua/article/view/24563

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