Lactoferrin-Containing Immunocomplexes Drive the Conversion of Human Macrophages from M2- into M1-like Phenotype

Lactoferrin-Containing Immunocomplexes Drive the Conversion of Human Macrophages from M2- into M1-like Phenotype

Macrophages are multifunctional cells that perform diverse roles in health and disease and considered the main source of inflammatory cytokines in affected joints of patients with rheumatoid arthritis (RA). M2 macrophages are well known as anti-inflammation and wound-healing cells; however, recent e...

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Bibliographic Details
Main Authors: Chen-Hui Gao, Hong-Liang Dong, Li Tai, Xiao-Ming Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
immune complex
lactoferrin
M2 macrophages
hyperactivity
rheumatoid arthritis
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00037/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00037/full

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