Heterologous expression of cyclodextrin glycosyltransferase from Paenibacillus macerans in Escherichia coli and its application in 2-O-α-D-glucopyranosyl-L-ascorbic acid production

Heterologous expression of cyclodextrin glycosyltransferase from Paenibacillus macerans in Escherichia coli and its application in 2-O-α-D-glucopyranosyl-L-ascorbic acid production

Abstract Background Cyclodextrin glucanotransferase (CGTase) can transform L-ascorbic acid (L-AA, vitamin C) to 2-O-α-D-glucopyranosyl-L-ascorbic acid (AA-2G), which shows diverse applications in food, cosmetic and pharmaceutical industries. Results In this study, the cgt gene encoding α-CGTase from...

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Bibliographic Details
Main Authors: Yujia Jiang, Jie Zhou, Ruofan Wu, Fengxue Xin, Wenming Zhang, Yan Fang, Jiangfeng Ma, Weiliang Dong, Min Jiang
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Biotechnology
Subjects:
Cyclodextrin glucanotransferase
Optimized codons
Glycosyl donors, 2-O-α-D-glucopyranosyl-L-ascorbic acid
Online Access:http://link.springer.com/article/10.1186/s12896-018-0463-9

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http://link.springer.com/article/10.1186/s12896-018-0463-9

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