Cobalt chloride compromises transepithelial barrier properties of CaCo-2 BBe human gastrointestinal epithelial cell layers

Cobalt chloride compromises transepithelial barrier properties of CaCo-2 BBe human gastrointestinal epithelial cell layers

Abstract Background Elevation of the transcription factor HIF-1 is a prominent mediator of not only processes that accompany hypoxia, but also the tumor microenvironment and tissue regeneration. This study uses mediators of “chemical hypoxia” to ask the question whether HIF-1α elevation in a healthy...

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Bibliographic Details
Main Authors: K. M. DiGuilio, M. C. Valenzano, E. Rybakovsky, J. M. Mullin
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Gastroenterology
Subjects:
CaCo-2
Tight junction
Claudin
Cobalt
HIF-1
Occludin
Online Access:http://link.springer.com/article/10.1186/s12876-017-0731-5

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http://link.springer.com/article/10.1186/s12876-017-0731-5

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