Attenuated Mycobacterium tuberculosis SO2 vaccine candidate is unable to induce cell death.

Attenuated Mycobacterium tuberculosis SO2 vaccine candidate is unable to induce cell death.

It has been proposed that Mycobacterium tuberculosis virulent strains inhibit apoptosis and trigger cell death by necrosis of host macrophages to evade innate immunity, while non-virulent strains induce typical apoptosis activating a protective host response. As part of the characterization of a nov...

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Bibliographic Details
Main Authors: Adriana Aporta, Ainhoa Arbues, Juan I Aguilo, Marta Monzon, Juan J Badiola, Alba de Martino, Nadia Ferrer, Dessislava Marinova, Alberto Anel, Carlos Martin, Julian Pardo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3446966?pdf=render

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http://europepmc.org/articles/PMC3446966?pdf=render

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