Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington’s disease

Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington’s disease

Huntington’s disease (HD) is a progressive, autosomal dominant neurodegenerative disorder affecting striatal neurons beginning in young adults with loss of muscle coordination and cognitive decline. Less appreciated is the fact that patients with HD also exhibit cardiac and respiratory dysfunction,...

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Bibliographic Details
Main Authors: Haikel Dridi, Xiaoping Liu, Qi Yuan, Steve Reiken, Mohamad Yehya, Leah Sittenfeld, Panagiota Apostolou, Julie Buron, Pierre Sicard, Stefan Matecki, Jérome Thireau, Clement Menuet, Alain Lacampagne, Andrew R. Marks
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-10-01
Series:JCI Insight
Subjects:
Cell biology
Therapeutics
Online Access:https://doi.org/10.1172/jci.insight.140614

Internet

https://doi.org/10.1172/jci.insight.140614

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