Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington’s disease
Huntington’s disease (HD) is a progressive, autosomal dominant neurodegenerative disorder affecting striatal neurons beginning in young adults with loss of muscle coordination and cognitive decline. Less appreciated is the fact that patients with HD also exhibit cardiac and respiratory dysfunction,...
Main Authors: | Haikel Dridi, Xiaoping Liu, Qi Yuan, Steve Reiken, Mohamad Yehya, Leah Sittenfeld, Panagiota Apostolou, Julie Buron, Pierre Sicard, Stefan Matecki, Jérome Thireau, Clement Menuet, Alain Lacampagne, Andrew R. Marks |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2020-10-01
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Series: | JCI Insight |
Subjects: | |
Online Access: | https://doi.org/10.1172/jci.insight.140614 |
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