An apicoplast localized ubiquitylation system is required for the import of nuclear-encoded plastid proteins.

Apicomplexan parasites are responsible for numerous important human diseases including toxoplasmosis, cryptosporidiosis, and most importantly malaria. There is a constant need for new antimalarials, and one of most keenly pursued drug targets is an ancient algal endosymbiont, the apicoplast. The api...

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Bibliographic Details
Main Authors: Swati Agrawal, Duk-Won D Chung, Nadia Ponts, Giel G van Dooren, Jacques Prudhomme, Carrie F Brooks, Elisadra M Rodrigues, John C Tan, Michael T Ferdig, Boris Striepen, Karine G Le Roch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3681736?pdf=render