Bradykinin B2 Receptors of dendritic cells, acting as sensors of kinins proteolytically released by Trypanosoma cruzi, are critical for the development of protective type-1 responses.

Bradykinin B2 Receptors of dendritic cells, acting as sensors of kinins proteolytically released by Trypanosoma cruzi, are critical for the development of protective type-1 responses.

Although the concept that dendritic cells (DCs) recognize pathogens through the engagement of Toll-like receptors is widely accepted, we recently suggested that immature DCs might sense kinin-releasing strains of Trypanosoma cruzi through the triggering of G-protein-coupled bradykinin B2 receptors (...

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Bibliographic Details
Main Authors: Ana Carolina Monteiro, Verônica Schmitz, Alexandre Morrot, Luciana Barros de Arruda, Fnu Nagajyothi, Alessandra Granato, João B Pesquero, Werner Müller-Esterl, Herbert B Tanowitz, Julio Scharfstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2098834?pdf=render

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http://europepmc.org/articles/PMC2098834?pdf=render

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