Multivariate Analysis of Preoperative Magnetic Resonance Imaging Reveals Transcriptomic Classification of de novo Glioblastoma Patients

Multivariate Analysis of Preoperative Magnetic Resonance Imaging Reveals Transcriptomic Classification of de novo Glioblastoma Patients

Glioblastoma, the most frequent primary malignant brain neoplasm, is genetically diverse and classified into four transcriptomic subtypes, i. e., classical, mesenchymal, proneural, and neural. Currently, detection of transcriptomic subtype is based on ex vivo analysis of tissue that does not capture...

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Bibliographic Details
Main Authors: Saima Rathore, Hamed Akbari, Spyridon Bakas, Jared M. Pisapia, Gaurav Shukla, Jeffrey D. Rudie, Xiao Da, Ramana V. Davuluri, Nadia Dahmane, Donald M. O'Rourke, Christos Davatzikos
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Computational Neuroscience
Subjects:
transcriptomic classification
glioblastoma
multivariate analysis
brain tumors classification
biomarkers
Online Access:https://www.frontiersin.org/article/10.3389/fncom.2019.00081/full

Internet

https://www.frontiersin.org/article/10.3389/fncom.2019.00081/full

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