CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits

CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits

CSF-contacting neurons are known to project to locomotor CPGs although their relevance to active locomotion is unclear. Here, the authors show that these cells constitute a mechanosensory organ relying on PKD2L1 channels to detect spinal cord curvature and modulate locomotor frequency in freely movi...

Full description

Bibliographic Details
Main Authors: Urs Lucas Böhm, Andrew Prendergast, Lydia Djenoune, Sophie Nunes Figueiredo, Johanna Gomez, Caleb Stokes, Sonya Kaiser, Maximilliano Suster, Koichi Kawakami, Marine Charpentier, Jean-Paul Concordet, Jean-Paul Rio, Filippo Del Bene, Claire Wyart
Format: Article
Language:English
Published: Nature Publishing Group 2016-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10866

Internet

https://doi.org/10.1038/ncomms10866

Similar Items