Investigations on Inhibitors of Hedgehog Signal Pathway: A Quantitative Structure-Activity Relationship Study

The hedgehog signal pathway is an essential agent in developmental patterning, wherein the local concentration of the Hedgehog morphogens directs cellular differentiation and expansion. Furthermore, the Hedgehog pathway has been implicated in tumor/stromal interaction and cancer stem cell. Nowadays...

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Bibliographic Details
Main Authors: Zhiwei Cao, Huiliang Li, Ruixin Zhu, Qi Liu, Jian Tang
Format: Article
Language:English
Published: MDPI AG 2011-05-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/12/5/3018/