Variation in RAD51 details a hub of functions: opportunities to advance cancer diagnosis and therapy [version 2; referees: 4 approved]
Loss of genome stability is one of the hallmarks of the enabling characteristics of cancer development. Homologous recombination is a DNA repair process that often breaks down as a prelude to developing cancer. Conversely, homologous recombination can be the Achilles’ heel in common anti-cancer ther...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2018-12-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/7-1453/v2 |