Elevated plasma angiopoietin-2 levels and primary graft dysfunction after lung transplantation.

INTRODUCTION:Primary graft dysfunction (PGD) is a significant contributor to early morbidity and mortality after lung transplantation. Increased vascular permeability in the allograft has been identified as a possible mechanism leading to PGD. Angiopoietin-2 serves as a partial antagonist to the Tie...

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Main Authors: Joshua M Diamond, Mary K Porteous, Edward Cantu, Nuala J Meyer, Rupal J Shah, David J Lederer, Steven M Kawut, James Lee, Scarlett L Bellamy, Scott M Palmer, Vibha N Lama, Sangeeta M Bhorade, Maria Crespo, Ejigayehu Demissie, Keith Wille, Jonathan Orens, Pali D Shah, Ann Weinacker, David Weill, Selim Arcasoy, David S Wilkes, Lorraine B Ware, Jason D Christie, Lung Transplant Outcomes Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3526525?pdf=render