Evaluation of cell-surface displayed synthetic consensus dengue EDIII cells as a potent oral vaccine candidate

Evaluation of cell-surface displayed synthetic consensus dengue EDIII cells as a potent oral vaccine candidate

Abstract Background Dengue is a rapidly spreading mosquito borne tropical viral disease affecting hundreds of millions of people across the globe annually. The dengue virus (DENV) includes four genetically distinct serotypes that cause serious life-threatening infections, including dengue hemorrhagi...

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Bibliographic Details
Main Authors: Jyotiranjan Bal, Hee-Young Jung, Luong Ngoc Nguyen, Jisang Park, Yong-Suk Jang, Dae-Hyuk Kim
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Microbial Cell Factories
Subjects:
Dengue
Oral vaccine
scEDIII
Saccharomyces cerevisiae
Surface display
Mucosal immunity
Online Access:http://link.springer.com/article/10.1186/s12934-018-0994-8

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http://link.springer.com/article/10.1186/s12934-018-0994-8

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