Use of pleiotropy to model genetic interactions in a population.

Systems-level genetic studies in humans and model systems increasingly involve both high-resolution genotyping and multi-dimensional quantitative phenotyping. We present a novel method to infer and interpret genetic interactions that exploits the complementary information in multiple phenotypes. We...

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Bibliographic Details
Main Authors: Gregory W Carter, Michelle Hays, Amir Sherman, Timothy Galitski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3469415?pdf=render