Chronic angiotensin-converting enzyme inhibition up-regulates mouse kidney growth arrest specific-6 protein and the AXL subfamily of receptor tyrosine kinases

Chronic angiotensin-converting enzyme inhibition up-regulates mouse kidney growth arrest specific-6 protein and the AXL subfamily of receptor tyrosine kinases

Introduction. Growth arrest specific-6 (GAS-6), a vitamin K-dependent protein, is a potential mediator in progressive and chronic renal disease, specifically as a mediator of abnormal mesangial cell proliferation. Nitric oxide and angiotensin II affect mesangial cell proliferation. However, an assoc...

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Bibliographic Details
Main Authors: Pei Chia Eng, Wendy Chen-Nee Chua, Valerie Suk Peng Chew, Peter Tsun Hon Wong, Jian Lin Yin, Brett Hambly, Craig Steven McLachlan
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2008-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320308098342

Internet

https://doi.org/10.1177/1470320308098342

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