Death Induced by CD95 or CD95 Ligand Elimination

Death Induced by CD95 or CD95 Ligand Elimination

CD95 (Fas/APO-1), when bound by its cognate ligand CD95L, induces cells to die by apoptosis. We now show that elimination of CD95 or CD95L results in a form of cell death that is independent of caspase-8, RIPK1/MLKL, and p53, is not inhibited by Bcl-xL expression, and preferentially affects cancer c...

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Bibliographic Details
Main Authors: Abbas Hadji, Paolo Ceppi, Andrea E. Murmann, Sonia Brockway, Abhinandan Pattanayak, Bhavneet Bhinder, Annika Hau, Shirley De Chant, Vamsi Parimi, Piotre Kolesza, JoAnne Richards, Navdeep Chandel, Hakim Djaballah, Marcus E. Peter
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714001491

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http://www.sciencedirect.com/science/article/pii/S2211124714001491

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