Ectodysplasin A Is Increased in Non-Alcoholic Fatty Liver Disease, But Is Not Associated With Type 2 Diabetes

Ectodysplasin A Is Increased in Non-Alcoholic Fatty Liver Disease, But Is Not Associated With Type 2 Diabetes

Ectodysplasin A (EDA) was recently identified as a liver-secreted protein that is increased in the liver and plasma of obese mice and causes skeletal muscle insulin resistance. We assessed if liver and plasma EDA is associated with worsening non-alcoholic fatty liver disease (NAFLD) in obese patient...

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Bibliographic Details
Main Authors: Jacqueline Bayliss, Geraldine J. Ooi, William De Nardo, Yazmin Johari Halim Shah, Magdalene K. Montgomery, Catriona McLean, William Kemp, Stuart K. Roberts, Wendy A. Brown, Paul R. Burton, Matthew J. Watt
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Endocrinology
Subjects:
ectodysplasin A
insulin resistance
hepatokine
type 2 diabetes (T2DM)
non-alcoholic fatty liver disease
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.642432/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.642432/full

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