miRNA expression profile changes in the peripheral blood of monozygotic discordant twins for epithelial ovarian carcinoma: potential new biomarkers for early diagnosis and prognosis of ovarian carcinoma

miRNA expression profile changes in the peripheral blood of monozygotic discordant twins for epithelial ovarian carcinoma: potential new biomarkers for early diagnosis and prognosis of ovarian carcinoma

Abstract Background Ovarian cancer is the second most common gynecologic cancer with high mortality rate and generally diagnosed in advanced stages. The 5-year disease-free survival is below 40%. MicroRNAs, subset of the non-coding RNA molecules, regulate the translation in post transcriptional leve...

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Bibliographic Details
Main Authors: Seref Bugra Tuncer, Ozge Sukruoglu Erdogan, Seda Kilic Erciyas, Mukaddes Avsar Saral, Betul Celik, Demet Akdeniz Odemis, Gozde Kuru Turkcan, Hulya Yazici
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Ovarian Research
Subjects:
Monozygotic twins
miRNA expression profiles
BRCA1 and BRCA2
Biomarkers
Online Access:http://link.springer.com/article/10.1186/s13048-020-00706-8

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http://link.springer.com/article/10.1186/s13048-020-00706-8

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