MDP Up-Regulates the Gene Expression of Type I Interferons in Human Aortic Endothelial Cells

MDP Up-Regulates the Gene Expression of Type I Interferons in Human Aortic Endothelial Cells

Muramyldipeptide (MDP), the minimum essential structure responsible for the immuno-adjuvant activity of peptidoglycan, is recognized by intracellular nuclear-binding oligomerization domain 2 (NOD2). Here, we obtained evidence that the treatment of human aortic endothelial cells (HAECs) with MDP up-r...

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Bibliographic Details
Main Authors: Xiumei Xie, Meifang Chen, Xiaobin Chen, Zhilin Xiao, Lina Zhou, Xueting Liu, Mei Yang, Qingshan Lv, Jinyue Hu
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Molecules
Subjects:
MDP
NOD2
interferon
endothelial cells
cytokine
Online Access:http://www.mdpi.com/1420-3049/17/4/3599/

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http://www.mdpi.com/1420-3049/17/4/3599/

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