Zn-Enhanced Asp-Rich Antimicrobial Peptides: N-Terminal Coordination by Zn(II) and Cu(II), Which Distinguishes Cu(II) Binding to Different Peptides
The antimicrobial activity of surfactant-associated anionic peptides (SAAPs), which are isolated from the ovine pulmonary surfactant and are selective against the ovine pathogen <i>Mannheimia haemolytica</i>, is strongly enhanced in the presence of Zn(II) ions. Both calorimetry and ITC m...
Main Authors: | Adriana Miller, Agnieszka Matera-Witkiewicz, Aleksandra Mikołajczyk, Joanna Wątły, Dean Wilcox, Danuta Witkowska, Magdalena Rowińska-Żyrek |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-06-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/13/6971 |
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