Induction of Drug Transporters Alters Disposition of Risperidone - A Study in Mice

Induction of Drug Transporters Alters Disposition of Risperidone - A Study in Mice

Pharmacokinetic interactions, e.g. modulation of drug transporters like P-glycoprotein at the blood-brain barrier, can be a reason for treatment non-response. This study focuses on the influence of induction of drug transporters on the disposition of the antipsychotic drugs risperidone and 9-hydroxy...

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Bibliographic Details
Main Authors: David Holthoewer, Christoph Hiemke, Ulrich Schmitt
Format: Article
Language:English
Published: MDPI AG 2010-06-01
Series:Pharmaceutics
Subjects:
drug transporter
P-glycoprotein
risperidone
9-hydroxyrisperidone
antipsychotics
disposition
Online Access:http://www.mdpi.com/1999-4923/2/2/258/

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http://www.mdpi.com/1999-4923/2/2/258/

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