Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells.

Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells.

Thymic medullary regions are formed in neonatal mice as islet-like structures, which increase in size over time and eventually fuse a few weeks after birth into a continuous structure. The development of medullary thymic epithelial cells (TEC) is dependent on NF-κB associated signaling though other...

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Main Authors: Rumi Satoh, Kiyokazu Kakugawa, Takuwa Yasuda, Hisahiro Yoshida, Maria Sibilia, Yoshimoto Katsura, Ben Levi, Jakub Abramson, Yoko Koseki, Haruhiko Koseki, Willem van Ewijk, Georg A Hollander, Hiroshi Kawamoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4720355?pdf=render

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http://europepmc.org/articles/PMC4720355?pdf=render

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