Positron Emission Tomography with [18F]FLT Revealed Sevoflurane-induced Inhibition of Neural Progenitor Cell Expansion in vivo

Positron Emission Tomography with [18F]FLT Revealed Sevoflurane-induced Inhibition of Neural Progenitor Cell Expansion in vivo

Neural progenitor cell expansion is critical for normal brain development and an appropriate response to injury. During the brain growth spurt, exposures to general anesthetics which either block the N-methyl D-aspartate receptor or enhance the γ-aminobutyric acid receptor type A can disturb neurona...

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Bibliographic Details
Main Authors: Shuliang eLiu, Merle G Paule, Xuan eZhang, Glenn eNewport, Tucker A. Patterson, Scott eApana, Marc eBerridge, Mackean Peter Maisha, William eSlikker Jr, Cheng eWang
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Neurology
Subjects:
proliferation
positron emission tomography (PET)
neural progenitor cell
sevoflurane
[18F]FLT
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00234/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00234/full

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