Roles of the Src tyrosine kinases Lck and Fyn in regulating gammadeltaTCR signal strength.

Lck and Fyn, members of the Src family of tyrosine kinases, are key components of the alphabetaTCR-coupled signaling pathway. While it is generally accepted that both Lck and Fyn positively regulate signal transduction by the alphabetaTCR, recent studies have shown that Lck and Fyn have distinct fun...

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Bibliographic Details
Main Authors: Renee M Laird, Sandra M Hayes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2811189?pdf=render