METTL3 Regulates Osteoblast Differentiation and Inflammatory Response via Smad Signaling and MAPK Signaling

METTL3 Regulates Osteoblast Differentiation and Inflammatory Response via Smad Signaling and MAPK Signaling

Osteoblasts are crucial bone-building cells that maintain bone homeostasis, whereas inflammatory stimuli can inhibit osteogenesis and activate inflammatory response. N6-methyladenosine (m<sup>6</sup>A) is the most abundant mRNA modification in eukaryotes and plays important roles in mult...

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Bibliographic Details
Main Authors: Yiwen Zhang, Xiaofei Gu, Di Li, Luhui Cai, Qiong Xu
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:International Journal of Molecular Sciences
Subjects:
mettl3
osteoblast differentiation
inflammatory response
smad
mapk
mrna stability
ythdf2
Online Access:https://www.mdpi.com/1422-0067/21/1/199

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https://www.mdpi.com/1422-0067/21/1/199

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