RECQL4, Negatively Regulated by miR-10a-5p, Facilitates Cell Proliferation and Invasion via MAFB in Ovarian Cancer

RECQL4, Negatively Regulated by miR-10a-5p, Facilitates Cell Proliferation and Invasion via MAFB in Ovarian Cancer

The high frequency of somatic copy number alterations, as opposed to point mutations, is considered a unique feature of ovarian cancer. Amplification-dependent overexpression of RecQ protein-like 4 (RECQL4), which participates in DNA replication and repair, mediates the development of various cancer...

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Bibliographic Details
Main Authors: Li Guo, Yingwei Li, Chen Zhao, Jiali Peng, Kun Song, Long Chen, Ping Zhang, Hanlin Ma, Cunzhong Yuan, Shi Yan, Yan Fang, Beihua Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
RECQL4
MAFB
miR-10a-5p
proliferation
invasion
ovarian cancer
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.524128/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.524128/full

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