Generation of a conditional transgenic mouse model expressing human Phospholipase A2 Receptor 1

Abstract The Phospholipase A2 Receptor 1 (PLA2R1) was first identified for its ability to bind some secreted PLA2s (sPLA2s). It belongs to the C-type lectin superfamily and it binds different types of proteins. It is likely a multifunctional protein that plays a role i) in inflammation and inflammat...

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Bibliographic Details
Main Authors: Sara Jaber, Delphine Goehrig, Philippe Bertolino, Amélie Massemin, Franck Bihl, Joëlle Chabry, Gérard Lambeau, David Vindrieux, David Bernard
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-64863-y