Cell death–associated lipid droplet protein CIDE-A is a noncanonical marker of endoplasmic reticulum stress

Cell death–associated lipid droplet protein CIDE-A is a noncanonical marker of endoplasmic reticulum stress

Secretory protein misfolding has been linked to ER stress and cell death. We expressed a TGrdw transgene encoding TG-G(2298)R, a misfolded mutant thyroglobulin reported to be linked to thyroid cell death. When the TGrdw transgene was expressed at low level in thyrocytes of TGcog/cog mice that experi...

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Bibliographic Details
Main Authors: Yoshiaki Morishita, Aaron P. Kellogg, Dennis Larkin, Wei Chen, Suryakiran Vadrevu, Leslie Satin, Ming Liu, Peter Arvan
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-04-01
Series:JCI Insight
Subjects:
Endocrinology
Online Access:https://doi.org/10.1172/jci.insight.143980

Internet

https://doi.org/10.1172/jci.insight.143980

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