The role of epigenetic modification in tumorigenesis and progression of pituitary adenomas: a systematic review of the literature.

Pituitary adenomas (PAs) are commonly occurring neoplasms with diverse endocrine and neurological effects. Although somatic gene mutations are uncommon in sporadic PAs, recent studies lend support to epigenetic modification as a potential cause of tumorigenesis and tumor progression.A systematic lit...

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Bibliographic Details
Main Authors: Matthew Pease, Chao Ling, William J Mack, Kai Wang, Gabriel Zada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3867353?pdf=render