Defective Phosphatidylglycerol Remodeling Causes Hepatopathy, Linking Mitochondrial Dysfunction to HepatosteatosisSummary

Background & Aims: Obesity promotes the development of nonalcoholic fatty liver diseases (NAFLDs), yet not all obese patients develop NAFLD. The underlying causes for this discrepancy remain elusive. LPGAT1 is an acyltransferase that catalyzes the remodeling of phosphatidylglycerol (PG), a mitoc...

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Bibliographic Details
Main Authors: Xiaoyang Zhang, Jun Zhang, Haoran Sun, Xueling Liu, Yue Zheng, Dan Xu, Jianing Wang, Dandan Jia, Xianlin Han, Feng Liu, Jia Nie, Yuguang Shi
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X19300116