Molecular signature of response and potential pathways related to resistance to the HSP90 inhibitor, 17AAG, in breast cancer

<p>Abstract</p> <p>Background</p> <p>HSP90 may be a favorable target for investigational therapy in breast cancer. In fact, the HSP90 inhibitor, 17AAG, currently has entered in phase II clinical trials as an anticancer agent in breast and other tumors. Since HSP90 inhib...

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Bibliographic Details
Main Authors: Benitez Javier, Gomez Gonzalo, Zajac Magdalena, Martínez-Delgado Beatriz
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Medical Genomics
Online Access:http://www.biomedcentral.com/1755-8794/3/44