Lipid rafts and Alzheimer’s disease: protein-lipid interactions and perturbation of signalling

Lipid rafts are membrane domains, more ordered than the bulk membrane and enriched in cholesterol and sphingolipids. They represent a platform for protein-lipid and protein-protein interactions and for cellular signalling events. In addition to their normal functions, including membrane trafficking,...

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Bibliographic Details
Main Authors: David A. Hicks, Natalia N Nalivaeva, Anthony J Turner
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Physiology
Subjects:
APP
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00189/full