Generation and Staging of Human Retinal Organoids Based on Self-Formed Ectodermal Autonomous Multi-Zone System

Generation and Staging of Human Retinal Organoids Based on Self-Formed Ectodermal Autonomous Multi-Zone System

Methods for stem cell-derived, three-dimensional retinal organoids induction have been established and shown great potential for retinal development modeling and drug screening. Herein, we reported an exogenous-factors-free and robust method to generate retinal organoids based on “self-formed ectode...

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Bibliographic Details
Main Authors: Jinyan Li, Yijia Chen, Shuai Ouyang, Jingyu Ma, Hui Sun, Lixia Luo, Shuyi Chen, Yizhi Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
human retinal organoid
RPE
ciliary margin
photoreceptor cell
SEAM system
retinogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.732382/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.732382/full

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