Inhibition of Exosome Release Sensitizes U937 Cells to PEGylated Liposomal Doxorubicin

Inhibition of Exosome Release Sensitizes U937 Cells to PEGylated Liposomal Doxorubicin

AimsAcute myeloblastic leukemia (AML) is the most common type of acute leukemia in adults. Despite numerous treatment strategies including chemotherapy and radiotherapy, a large number of patients do not respond to treatment and experience relapse. The main problem of these patients is the developme...

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Main Authors: Shirin Hekmatirad, Milad Moloudizargari, Ali Akbar Moghadamnia, Sohrab Kazemi, Mousa Mohammadnia-Afrouzi, Maryam Baeeri, Fatemeh Moradkhani, Mohammad Hossein Asghari
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
extracellular vesicles (EVs)
exosome
cancer
drug resistance
liposomal doxorubicin
virtual screening
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.692654/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.692654/full

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