Increased expression of Polδ does not alter the canonical replication program in vivo [version 2; peer review: 2 approved]
Background: In vitro experiments utilising the reconstituted Saccharomyces cerevisiae eukaryotic replisome indicated that the efficiency of the leading strand replication is impaired by a moderate increase in Polδ concentration. It was hypothesised that the slower rate of the leading strand synthesi...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wellcome
2021-05-01
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| Series: | Wellcome Open Research |
| Online Access: | https://wellcomeopenresearch.org/articles/6-44/v2 |