Trans-Corneal Subretinal Injection in Mice and Its Effect on the Function and Morphology of the Retina.

To introduce a practical method of subretinal injection in mice and evaluate injection-induced retinal detachment (RD) and damage using a dynamic imaging system, electrophysiology, and histology.After full dilation of a 2-month-old C57BL/6J mouse pupil, the cornea near the limbus was punctured with...

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Bibliographic Details
Main Authors: Yan Qi, Xufeng Dai, Hua Zhang, Ying He, Yangyang Zhang, Juanjuan Han, Ping Zhu, Yuxin Zhang, Qinxiang Zheng, Xia Li, Chen Zhao, Jijing Pang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4552822?pdf=render