Episodic, transient systemic acidosis delays evolution of the malignant phenotype: Possible mechanism for cancer prevention by increased physical activity

<p>Abstract</p> <p>Background</p> <p>The transition from premalignant to invasive tumour growth is a prolonged multistep process governed by phenotypic adaptation to changing microenvironmental selection pressures. Cancer prevention strategies are required to interrupt...

Full description

Bibliographic Details
Main Authors: Maini Philip K, Smallbone Kieran, Gatenby Robert A
Format: Article
Language:English
Published: BMC 2010-04-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/5/1/22