An assessment of the role of DNA adenine methyltransferase on gene expression regulation in E coli.

N6-Adenine methylation is an important epigenetic signal, which regulates various processes, such as DNA replication and repair and transcription. In gamma-proteobacteria, Dam is a stand-alone enzyme that methylates GATC sites, which are non-randomly distributed in the genome. Some of these overlap...

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Bibliographic Details
Main Author: Aswin Sai Narain Seshasayee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1804101?pdf=render