Computing power and sample size for case-control association studies with copy number polymorphism: application of mixture-based likelihood ratio test.

Computing power and sample size for case-control association studies with copy number polymorphism: application of mixture-based likelihood ratio test.

Recent studies suggest that copy number polymorphisms (CNPs) may play an important role in disease susceptibility and onset. Currently, the detection of CNPs mainly depends on microarray technology. For case-control studies, conventionally, subjects are assigned to a specific CNP category based on t...

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Bibliographic Details
Main Authors: Wonkuk Kim, Derek Gordon, Jonathan Sebat, Kenny Q Ye, Stephen J Finch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2566806?pdf=render

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http://europepmc.org/articles/PMC2566806?pdf=render

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