Endothelium-dependent relaxation and angiotensin II sensitivity in experimental preeclampsia.

OBJECTIVE: We investigated endothelial dysfunction and the role of angiotensin (Ang)-II type I (AT1-R) and type II (AT2-R) receptor in the changes in the Ang-II sensitivity in experimental preeclampsia in the rat. METHODS: Aortic rings were isolated from low dose lipopolysaccharide (LPS) infused pre...

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Bibliographic Details
Main Authors: Anne Marijn van der Graaf, Marjon J Wiegman, Torsten Plösch, Gerda G Zeeman, Azuwerus van Buiten, Robert H Henning, Hendrik Buikema, Marijke M Faas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3819278?pdf=render