Bisphosphonates Target B Cells to Enhance Humoral Immune Responses

Bisphosphonates Target B Cells to Enhance Humoral Immune Responses

Bisphosphonates are a class of drugs that are widely used to inhibit loss of bone mass in patients. We show here that the administration of clinically relevant doses of bisphosphonates in mice increases antibody responses to live and inactive viruses, proteins, haptens, and existing commercial vacc...

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Bibliographic Details
Main Authors: Elena Tonti, Nereida Jiménez de Oya, Gabriele Galliverti, E. Ashley Moseman, Pietro Di Lucia, Angelo Amabile, Stefano Sammicheli, Marco De Giovanni, Laura Sironi, Nicolas Chevrier, Giovanni Sitia, Luigi Gennari, Luca G. Guidotti, Ulrich H. von Andrian, Matteo Iannacone
Format: Article
Language:English
Published: Elsevier 2013-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713005123

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http://www.sciencedirect.com/science/article/pii/S2211124713005123

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