IL-18 induces airway hyperresponsiveness and pulmonary inflammation via CD4+ T cell and IL-13.

IL-18 induces airway hyperresponsiveness and pulmonary inflammation via CD4+ T cell and IL-13.

IL-18 plays a key role in the pathogenesis of pulmonary inflammatory diseases including pulmonary infection, pulmonary fibrosis, lung injury and chronic obstructive pulmonary disease (COPD). However, it is unknown whether IL-18 plays any role in the pathogenesis of asthma. We hypothesized that overe...

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Bibliographic Details
Main Authors: Masanori Sawada, Tomotaka Kawayama, Haruki Imaoka, Yuki Sakazaki, Hanako Oda, Shin-ichi Takenaka, Yoichiro Kaku, Koichi Azuma, Morihiro Tajiri, Nobutaka Edakuni, Masaki Okamoto, Seiya Kato, Tomoaki Hoshino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3558507?pdf=render

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http://europepmc.org/articles/PMC3558507?pdf=render

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