Long-Term Moderate Exercise Combined with Metformin Treatment Induces an Hormetic Response That Prevents Strength and Muscle Mass Loss in Old Female Wistar Rats

Sarcopenia is a syndrome characterized by a progressive and generalized skeletal muscle mass and strength loss, as well as a poor physical performance, which as strongly been associated with aging. Sedentary lifestyle in the elderly contributes to this condition; however, physical activity improves...

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Main Authors: David Hernández-Álvarez, Beatriz Mena-Montes, Rafael Toledo-Pérez, Gibrán Pedraza-Vázquez, Stefanie Paola López-Cervantes, Alfredo Morales-Salazar, Edith Hernández-Cruz, Roberto Lazzarini-Lechuga, Roman Royer Vázquez-Cárdenas, Silvia Vilchis-DeLaRosa, Pedro Posadas-Rodríguez, Roberto Santín-Márquez, Oscar Rosas-Carrasco, Alejandra Ibañez-Contreras, Adriana Alarcón-Aguilar, Norma Edith López-Díazguerrero, Armando Luna-López, Mina Königsberg
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/3428543